Emily Corbally Langley-Epilepsy-(Ireland)

Name: Emily Corbally Langley
Sex: Female
Nationality: Irish
Age: 18Y
Diagnosis: 1. Brain Injury 2. Epilepsy
Discharge Date: 2019/04/05

Before treatment:
At the age of 2 and a half, the patient had no inducement of fever, accompanied by systemic convulsions, and immediately went to the hospital to give antiepileptic drugs and anti-infective treatment (the specific drug was unknown). The patient had frequent systemic seizures, loss of consciousness, systemic convulsions, lasting 1-2 minutes at a time, repeated use of antiepileptic drugs is not effective.Her limb functions and cognitive function were affected. She could not speak, lost her comprehension, increased systemic muscle tone and showed spasm all over the body. After discharge, the patient's mother gave the patient diet adjustment and physical therapy, the patient's limb tension was improved, epilepsy was small seizure, absence, only the eyes occasionally involuntary movement, lasted for a few seconds. There has been an improvement in understanding. At present, patients with limb flexion deformity, high tension, can not speech, only can shout "MAMA", can not take care of herself.
Patients sleep more since the spontaneous disease, eat paste diet, defecate and urinate functions are basically normal.

Admission PE:
Bp: 116/77mmHg, Hr: 87/min, breathing rate: 19/min, body temperature: 37.1 degrees. Height 146cm, weight 31Kg. very thin and nutrition status was poor. There is no injury or bleeding spots of his skin and mucosa, no blausucht, no throat congestion. Chest development was normal, the respiratory sounds in both lungs were clear, there was no dry or moist rales. The heart beat is powerful with regular cardiac rhythm, with no obvious murmur in the valves. The abdomen was plate and soft, with no masses or tenderness. The liver and spleen were normal. no edema of lower limbs.

Nervous System Examination:
Patient was alert, she only can make sound MAMA. She could not cooperate the examination of memory, calculation, orientation or comprehensive ability examinations. Bilateral pupil diameter 3mm, react well to light. Eyeballs can move freely. she could not cooperate the eyesight, visual field or nystagmus examination. The bilateral forehead wrinkle and nasolabial fold are symmetrical, she could not cooperate with cranial nerve function examination, her neck, back  and waist muscles were weak, she could keep head up straightly occasionally, she could not sit up, roll over in bed or crawl. She could not cooperate 4 limbs muscle power exam, 4 limbs muscle tone were high, the limbs had bending malformation, right elbow joint and wrist joint can open around 140 degree, left elbow joint and wrist joint can open around 90 degree, lower limbs knee joints can open 120-130 degree, the ankle joint and feet had severe deformation, can not recover to functional position, her fingers could open passively. 4 limbs tendon reflex was normal, bilateral palm-jaw reflex was negative, the Hoffmann sign and Rossilimo sign of both sides were negative, bilateral Babinski sign was negative, she could not cooperate sensory system and coordinate movement examination, the meningeal irritation sign was negative.

Treatment:
After the admission, she received 3 nerve regeneration treatments(neural stem cells and mesenchymal stem cells) to repair her damaged nerves, replace dead nerves, nourish nerves(ganglioside, nerve growth factors and neurotrophic factors), improve body environment, regulate her immune system and improve blood circulation, with rehabilitation training.   

Post-treatment:
After 14 days’ treatment, her brain function was better, she had better attention, she could focus on others and surrounding persons more time, her sitting posture was much stable, she neck support ability improved, and she start to show head movement. Her body was more relaxed than before, her right arm elbow angle increase than before , her joints are more flexible.

E-mail:
Date: 2019/9/16

Hello dr.Liu I am very sorry for the delay but trying to get my results from the blood test here have been very hard I have waited for the last month and have been emailed to say all is good with the results I have asked for them to be sent to myself or you and again I am waiting on a reply.  Since myself and Emily have returned she continues to make progress her hands and feet are more comfortable and her spasms have subsided she has put on weight and fat around her whole body, since Emily became unwell this is the best she has ever been.  I am so very happy I decided to take the trio to China I can’t thank you all enough.  I will chase up the doctors here, they have shown no concern here and are taking their time to do anything for me.  I will get back in touch as soon as possible.  Thank you very much for your kind patience.  Suzanne and Emily

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